Path followed:
1. Is the fault in the components that perform any physical action?
Answer: No
2. Is the faulty component part of the mechanism’s body?
Answer: No
3. Is the faulty component in the fuel system?
Answer: Yes
4. Is the fault in the fuel filtration system?
Answer: Yes
5. Is the fault in the fuel filtration components?
Answer: Yes
6. Is the fault in the components responsible for removing fuel consumption by products?
Answer: Yes
7. Can other parts of the mechanism be used to minimize the effect of the fault?
Answer: No
8. Is any debris cleared from the damaged area?
Answer: Yes
98) Oyster toadfish, Opsanus tau
Oyster toadfish can be found from Maine to the Caribbean Sea (Froese). The Oyster toadfish has the capability of regenerating its kidney if it was to get damaged.
Soon after the Toadfishes kidney has been injured macrophages will converge on the wound and clear the dead cells and debris away. Next the kidney will start producing certain signals to initiate renal regeneration, which are myc, Pax-2, and insulin-like growth factor-1 (Reimschuessel). The signals target epithelial cells to migrate to the injured portion of the kidney and start proliferating. At first these cells are used to repopulate the basophilic epithelial basement membrane (Reimschuessel). Then the fish undergoes a nephron neogenesis phase to reestablish the nephrons. Renal vesicles, S-shaped tubules, and tubular outgrowths are made from the basophilic epithelium cells (Reimschuessel). All of those structures fuse with the collecting duct to form the various kidney structures. Then the Bowman’s capsule is formed using the epithelial parts. Once all of the structures have been formed the cells will stop proliferating and disperse away from the injured site.
Froese, Rainer. “Opsanus Tau.” Opsanus Tau, Oyster Toadfish Summary. Fishbase, 19 May 2014. Web. 27 Dec. 2014.
http://www.fishbase.org/summary/3069
Reimschuessel, Renate. “A Fish Model of Renal Regeneration and Development.” ILAR Journal 42.4 (2001): 285-91.Oxford Journals. Web. 27 Dec. 2014.
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