Replace 89

Path followed:

1. Is the fault in the components that perform any physical action?

Answer: No

2. Is the faulty component part of the mechanism’s body?

    Answer: Yes

3. Is the faulty component in the structure of the mechanism? 

    Answer: Yes

4. Does the fault appear in components that provide rigidity to the mechanism?

    Answer: Yes

5. Can the faulty component be removed from the mechanism?

    Answer: No

6. Is the fault in load bearing components?

    Answer:Yes

7. Do multiple versions of the components exist for the faulty component?

    Answer: No

8. Can the mechanism continue to function until the component is replaced?

    Answer: No

9. Do debris need to be cleared from the damaged area?

    Answer: No

 

89) Common leopard gecko, Eublepharis macularius

Common leopard geckos can be found in the Middle East (Woods). These geckos are able to autotomize their tails if they get in danger. The leopard gecko has the ability of regenerating its tail after it is lost from an accident or foul play.

After tail is lost the spinal cord retracts further into the body and a blood clot is produced at the end to keep it from bleeding out. The walls closest to the wound essentially collapse and cover the wound area. A blastula is formed over the wound and houses epithelial and endothelial cells, myoblasts, osteoclasts, and chondroclasts (McLean & Vickaryous). Next, epithelial cells will proliferate and form the various layers of tissue in the tail. The epithelial cells are dedifferentiated and then re-differentiated into nerve cells that will form the axons of the nervous system in the tail. Endothelial cells are also seen proliferating and differentiating into blood vessels in the epithelium.  Some of the cells in the blastema also differentiate into myoblasts that will proliferate and help the tail grow larger and longer by forming the cartilage
(McLean & Vickaryous). As the tail is getting longer osteoclasts mature into chondroclasts and form the bone structure in the tail. Once the tail has elongated the epithelial cells become keratinized and epidermal scales begin to form and the skin gets fully pigmented (McLean & Vickaryous). As soon as the tail has been fully formed from the various types of cells proliferating and differentiating the blastula will disintegrate and the cells will go back into the quiescent stage of mitosis.

Woods, Vickie. “Eublepharis Macularius.” ADW:Eublepharis Macularius.Animal Diversity Web, 20 Jan. 2001. Web. 20 Dec. 2014.

http://animaldiversity.org/accounts/Eublepharis_macularius/

McLean, Katherine E., and Matthew K. Vickaryous. “A Novel Amniote Model of Epimorphic Regeneration: The Leopard Gecko, Eublepharis Macularius.” BMC Developmental Biology 11 (2011): 50. BMC Developmental Biology. Web. 20 Dec. 2014.

http://www.biomedcentral.com/1471-213X/11/50