Path followed:
1. Is the fault in the components that perform any physical action?
Answer: Yes
2. Is the fault in components that move?
Answer: No
3. Is the fault in the mechanisms controls?
Answer: Yes
4. Is the fault in the components responsible for sending signals?
Answer: Yes
5. Is the fault only limited to non-sensory components?
Answer: No
75) Zebrafish, Danio rerio
Zebrafish can be found in the tropical fresh waters of northern India, northern Pakistan, Nepal, and South Asia. They can grow up to 4-5 centimeters in length and get their name from stripes on their body (Hamel & Mercier). Zebrafish can also regenerate parts of their brain if it was to get injured.
Zebrafish are different from mammals in their regenerative capabilities when dealing with the brain because Zebrafish are continually proliferating their cells in progenitor zones in the brain. The progenitor zone houses stem/progenitor cells that can differentiate into whatever cell is needed at certain times (Kroehne et al.). They usually turn into radial glia progenitor cells that proliferate and generate neuroblasts, which help form neurons in the brain (Kroehne et al.). Once the brain is injured there needs to be a release of cysteinyl leukotriene to stimulate an acute inflammation at the site of injury or the brain can not regenerate itself (Kyritsis et al.). The acute inflammation has been show to induce neural progenitors and neurogenesis (Kyritsis et al.). Once the brain has been healed the inflammation will reduce and become non-existent and then the progenitor cells will stop proliferating and differentiating.
Hamel, J.-F. & Mercier, A. 2013. Apostichopus japonicus. The IUCN Red List of Threatened Species. Version 2014.3. Web. 13 Dec. 2014.
http://www.iucnredlist.org/details/180424/0
Kyritsis, N., C. Kizil, S. Zocher, V. Kroehne, J. Kaslin, D. Freudenreich, A. Iltzsche, and M. Brand. “Acute Inflammation Initiates the Regenerative Response in the Adult Zebrafish Brain.” Science 338.6112 (2012): 1353-356. NCBI. Web. 14 Dec. 2014.
http://www.ncbi.nlm.nih.gov/pubmed/23138980
Kroehne, Volker, Dorian Freudenreich, Stefan Hans, Jan Kaslin, and Michael Brand. “Regeneration of the Adult Zebrafish Brain from Neurogenic Radial Glia-type Progenitors.” Development 138 (2011): 4831-841.Development and Stem Cells. Web. 14 Dec. 2014.
Recent Comments