Path followed:
- Is the fault in the components that perform any physical action?
Answer: Yes
- Is the fault in components that move?
Answer: Yes
- Is the fault in components that make the mechanism move?
Answer: Yes
- Is the faulty component designed to move the mechanism around?
Answer: No
- Is the faulty component a joint?
Answer: No
- Is the faulty component needed for stability?
Answer: No
- Do the characteristics of the system change after regeneration?
Answer: Yes
63) Rat, Rattus
Rats can be found all over the world and can live for up to 5 years (“Rat”). Rats have the ability of regenerating amputated limb buds while still in the embryo.
When babies are initially starting to grow in the embryo all of the cells are multipotent. Multipotent means that the cells can differentiate into any type of cell and create any structure of the body. If a limb happens to get amputated while the baby is still developing in the embryo the limb can be regenerated. A blastema-like structure forms over the wound site which house ectodermal and mesenchyme cells (Deuchar). The ectodermal cells proliferate and differentiate to form an intact ectodermal epithelium which covers the wound site (Deuchar). The mesenchyme cells also proliferate and form the bud where the limb will continue to grow out of.
“Rat.” Rat (tus Tus). Http://a-z-animals.com/, 2013. Web. 7 Dec. 2014.
http://a-z-animals.com/animals/rat/
Deuchar, Elizabeth M. “Regeneration of Amputated Limb-buds in Early Rat Embryos.” Journal of Embryology and Experimental Morphology 35.2 (1976): 345-54. Development. Web. 7 Dec. 2014.
http://dev.biologists.org/content/35/2/345.full.pdf