Replace 25

Path 1:

1.   Is the fault in the components that perform any physical action?

       Answer: No

2.   Is the faulty component part of the mechanism’s body?

Answer: No

3.   Is the faulty component in the fuel system?

Answer: Yes

4.   Is the fault in the fuel filtration system?

Answer: Yes

5.   Is the fault in the fuel filtration components?

Answer: Yes

6.   Is the fault in the components responsible for removing fuel consumption by products?

Answer: No

7.   Is removal of the damaged section possible?

       Answer: No

8.   Can other parts of the mechanism be used to minimize the effect of the fault?

Answer: Yes

9.   Is there a trigger event to begin the replacement of the component?

Answer: Yes

 

Path 2:

1.   Is the fault in the components that perform any physical action?

Answer: Yes

2.   Is the fault in components that move?

Answer: No

3.   Is the fault in the mechanisms controls?

Answer: Yes

4.   Is the fault in the components responsible for sending signals?

Answer: No

5.   Does the faulty component control any other functions in the mechanism?

Answer: No

6.   Does the fault effect all components responsible for transmitting sensory data?

Answer: Yes

7.   Can the faulty component be replaced regardless of its location in the mechanism?

Answer: No

 

25) Zebrafish, Danio rerio

Zebrafish can be found in the tropical fresh waters of northern India, northern Pakistan, Nepal, and South Asia. They can grow up to 4-5 centimeters in length and get their name from stripes on their body (Hamel & Mercier). Zebrafish also have the remarkable ability of liver regeneration.

After the liver in the Zebrafish has lost hepatocytes from sort of injury, biliary cells have been found to migrate to wound site. The biliary cells dedifferentiate through a process that was initiated by Notch signaling, which in turn activated cholangiocytes to dedifferentiate the cells (He et al.). Once the cells dedifferentiated, they would proliferate and re-differentiate into hepatocytes. The hepatocytes would then attach to the liver and gradually increase the liverÕs size. Once the liver is at its maximum size the biliary cells would stop dedifferentiated and disperse back to where it came from.

Hamel, J.-F. & Mercier, A. Apostichopus japonicus. The IUCN Red List of Threatened Species. Version 2014.3, 2013. Web. 27 Nov. 2014.

http://www.iucnredlist.org/details/180424/0

He, J., H. Lu, Q. Zou, and L. Luo. “Regeneration of Liver after Extreme Hepatocyte Loss Occurs Mainly
via Biliary Transdifferentiation in Zebrafish.” Gastroenterology 146.3 (2014): 789-800. NCBI. Web. 28 Nov. 2014.

http://www.ncbi.nlm.nih.gov/pubmed/24315993