Replace 104

Path 1:

1.   Is the fault in the components that perform any physical action?

Answer: No

2.   Is the faulty component part of the mechanism’s body?

       Answer: No

3.   Is the faulty component in the fuel system?

Answer: Yes

4.   Is the fault in the fuel filtration system?

       Answer: Yes

5.   Is the fault in the fuel filtration components?

Answer: Yes

6.   Is the fault in the components responsible for removing fuel consumption by products?

Answer: Yes

7.   Can other parts of the mechanism be used to minimize the effect of the fault?

       Answer: No

8.   Is any debris cleared from the damaged area?

Answer: Yes

 

Path 2:

1.   Is the fault in the components that allow the mechanism to perform its mission?

Answer: Yes

2.   Is the fault in components that move?

Answer: Yes

3.   Is the fault in components that make the mechanism move?

Answer: Yes

4.   Is the faulty component a part of a larger mechanism designed to move?

Answer: No

5.   Is the component designed to move objects, including the mechanism?

Answer: Yes

6.   Is the fault component not needed for stability?

Answer: No

7.   Does the component manipulate other objects?

Answer: Yes

8.   Does the adaptation occur in stages?

       Answer: No

104) Nile tilapia, Oreochromis niloticus

Nile tilapias originated from Africa but have been spread to other tropic and subtropic areas (ÒTilapiaÓ). Nile tilapias have the ability of regenerating their kidney if it were to get damaged in some way.

Soon after a tilapias kidney is damaged it will have a phase in which macrophages will phagocytize dead cells or other debris. After the cells and debris are cleared away the kidney will start producing signals that will initiate kidney regeneration. Those signals include myc, Pax-2, and insulin-like growth facto-1 (Reimschuessel). These signals trigger epithelial cells to migrate to the wounded spot on the kidney and start to proliferate. The cells proliferate to repopulate the basophilic epithelial basement membrane (Reimschuessel). Then the tilapia has a nephron neogenesis phase to reestablish the nephrons in the regenerated portion. The basophilic epithelium cells are used to form renal vesicles, S-shaped tubules, and tubular outgrowths which fuse with the collecting duct (Reimschuessel). The BowmanÕs capsule will form from the epithelial parts as well. Once all of the structures have formed the cells will stop proliferating and migrate away from the previously wounded site.

“Tilapia.” Tilapia. Aller Aqua, 2014. Web. 28 Dec. 2014.

http://aller-aqua.com/cms/front_content.php?idcat=187

Reimschuessel, Renate. “A Fish Model of Renal Regeneration and Development.” ILAR Journal 42.4 (2001): 285-91.Oxford Journals. Web. 28 Dec. 2014.

http://ilarjournal.oxfordjournals.org/content/42/4/285.full