Replace 102

Path followed:

1.   Is the fault in the components that perform any physical action?

Answer: No

2.   Is the faulty component part of the mechanism’s body?

Answer: No

3.   Is the faulty component in the fuel system?

Answer: Yes

4.   Is the fault in the fuel filtration system?

Answer: Yes

5.   Is the fault in the fuel filtration components?

Answer: Yes

6.   Is the fault in the components responsible for removing fuel consumption by products?

Answer: Yes

7.   Can other parts of the mechanism be used to minimize the effect of the fault?

       Answer: No

8.   Is any debris cleared from the damaged area?

Answer: Yes

102) Rainbow trout, Oncorhynchus mykiss

Rainbow trout are native to North America but have been introduced to every other continent besides Antarctica (ÒRainbow-Trout-or-SteelheadÓ). Rainbow trout have the ability of regenerating their kidney if it were to get damaged.

Soon after the rainbow trout has kidney damage macrophages will converge on the injured site and phagocytize the dead cells and other debris. After this stage the kidney will start producing signals that will help the kidney regenerate. The signals are myc, Pax-2, and insulin-like growth factor-1 (Reimschuessel). These signals help initiate the epithelial cells to migrate and start proliferating at the injured section. The cells are used to repopulate the basophilic epithelial basement membrane (Reimschuessel). Then the fish will undergo a nephron neogenesis phase to reestablish the nephrons in the newly regenerated section. The basophilic epithelium cells are used to form the renal vesicles, S-shaped tubules, and tubular outgrowths which fuse with the collecting ducts (Reimschuessel). The BowmanÕs capsule is also made by using the epithelial cells and parts. Once all of the structures for the kidney have been formed the cells will disperse away from the previously injured section and stop proliferating.

“Rainbow-Trout-or-Steelhead.” Rainbow-Trout-or-Steelhead – National Wildlife Federation. National Wildlife Federation, 2014. Web. 28 Dec. 2014.

http://www.nwf.org/wildlife/wildlife-library/amphibians-reptiles-and-fish/rainbow-trout-or-steelhead.aspx

Reimschuessel, Renate. “A Fish Model of Renal Regeneration and Development.” ILAR Journal 42.4 (2001): 285-91.Oxford Journals. Web. 28 Dec. 2014.

http://ilarjournal.oxfordjournals.org/content/42/4/285.full