Repair 16

Path followed:

1.   Are there any external resources that can be used by the damaged component?

      Answer: No

2.   Is there any foreign material present?

Answer: Yes

3.   Is the foreign material removable?

Answer: No

4.   Can the foreign material be destroyed?

Answer: Yes

16) Vibrio cholerae

Water can become contaminated with the bacterium Vibrio cholerae. Once the individual ingests the bacteria it will colonize in the intestines (University of York.). It is able to survive in the intestines by eating the  sialic acid sugars on the surface of the gut cells (University of York.). As it proliferates into many bacterium it is able to secrete a toxin which causes havoc in the body. The major problem is diarrhea because if left untreated the individual could become severely dehydrated and lose a lot of its vitamins and minerals leading to death. Once the body has been infected with the bacterium the innate immune response will be triggered allowing natural defense mechanisms to converge on the bacterium and slow or hinder the proliferation (Rollwagen, Florence M). The acquired immune response will then be triggered and release Immunoglobulin A antibodies which bind to the bacteria signaling to the macrophages what to destroy (Rollwagen, Florence M). The immune system along with fluids will allow the individual to recover.

University of York. “University of York Scientists Reveal How Cholera Attacks Body.” News-Medical.net. News Medical, 30 Jan. 2012. Web. Retrieved March 5, 2015, from

http://www.news-medical.net/news/20120130/University-of-York-scientists-reveal-how-cholera-attacks-body.aspx

Rollwagen, Florence M. “Immune System Response Agaisnt Cholera.” AE Biology. All Experts, 24
May 2009. Web. Retrieved March 4, 2015, from

http://en.allexperts.com/q/Biology-664/2009/5/Immune-system-response-against.htm.